Trucks stall on the road to this plateau 16,597 feet up in the Atacama Desert, where scientists are installing one of the world’s largest ground-based astronomical projects. Heads ache. Noses bleed. Dizziness overcomes the researchers toiling in the shadow of the Licancabur volcano.

“Then there’s what we call ‘jelly legs,’ ” said Diego García-Appadoo, a Spanish astronomer studying galaxy formation. “You feel shattered, as if you ran a marathon.”

Still, the same conditions that make the Atacama, Earth’s driest desert, so inhospitable make it beguiling for astronomy. In northern Chile, it is far from big cities, with little light pollution. Its arid climate prevents radio signals from being absorbed by water droplets. The altitude, as high as the Himalaya base camps for climbers preparing to scale Mount Everest, places astronomers closer to the heavens.

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