The Human Immune System in Space

When the space shuttle Atlantis touched down in the summer of 2011 at Cape Canaveral, closing the book on the U.S. shuttle program, a team of U.S. Army researchers stood at the ready, eager to get their gloved hands on a small device in the payload that housed a set of biological samples. On Monday, April 22, at the Experimental Biology 2013 conference in Boston, the team will present the results of nearly two years' worth of study on those samples, results that shed light on how the human immune system responds to stress and assaults while in space -- and maybe here on Earth.

"Weakening of the immune system associated with spaceflight is an area that needs a thorough investigation," said Marti Jett, director of the Integrative Systems Biology Program at the U.S. Army Medical Command. "Astronauts subjected to microgravity have shown a significant immune weakening. Furthermore, microgravity has been shown to enhance bacterial virulence while depressing the immune response."