A new resource will allow scientists to explore the anatomy of a single brain in three dimensions at far greater detail than before, a possibility its creators hope will guide the quest to map brain activity in humans. The resource, dubbed the BigBrain, was created as part of the European Human Brain Project and is freely available online for scientists to use.
The researchers behind the BigBrain, led by Katrin Amunts at the Research Centre Jülich and the Heinrich Heine University Düsseldorf in Germany, imaged the brain of a healthy deceased 65-year-old woman using MRI and then embedded the brain in paraffin wax and cut it into 7,400 slices, each just 20 micrometers thick. Each slice was mounted on a slide and digitally imaged using a flatbed scanner.
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