An unmanned American Falcon-9 rocket has broken apart in flames minutes after lifting off from Cape Canaveral in Florida.
Debris from the SpaceX vehicle tumbled out of the sky into the Atlantic Ocean.
The rocket, which had 18 straight successes prior to Sunday's flight, was in the process of sending a cargo ship to the International Space Station.
As well as carrying supplies for the astronauts, the Falcon had also been transporting a new docking port.
"The vehicle has broken up," said Nasa commentator George Diller, as TV images showed the white rocket falling to pieces.
"We appear to have had a launch vehicle failure," he added.
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