In the same underground observatory in Japan where, 18 years ago, neutrinos were first seen oscillating from one “flavor” to another — a landmark discovery that earned two physicists the 2015 Nobel Prize — a tiny anomaly has begun to surface in the neutrinos’ oscillations that could herald an answer to one of the biggest mysteries in physics: why matter dominates over antimatter in the universe.

The anomaly, detected by the T2K experiment, is not yet pronounced enough to be sure of, but it and the findings of two related experiments “are all pointing in the same direction,” said Hirohisa Tanaka of the University of Toronto, a member of the T2K team who presented the result to a packed audience in London earlier this month.

“A full proof will take more time,” said Werner Rodejohann, a neutrino specialist at the Max Planck Institute for Nuclear Physics in Heidelberg who was not involved in the experiments, “but my and many others’ feeling is that there is something real here.”

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