There might be no natural limit to how long humans can live — at least not one yet in sight — contrary to the claims of some demographers and biologists.

That’s according to a statistical analysis published Thursday in Science1 on the survival probabilities of nearly 4,000 ‘super-elderly’ people in Italy, all aged 105 and older.

A team led by Sapienza University demographer Elisabetta Barbi and University of Roma Tre statistician Francesco Lagona, both based in Rome, found that the risk of death — which, throughout most of life, seems to increase as people age — levels off after age 105, creating a ‘mortality plateau’. At that point, the researchers say, the odds of someone dying from one birthday to the next are roughly 50:50 (see ‘Longevity unlimited’).

“If there is a mortality plateau, then there is no limit to human longevity,” says Jean-Marie Robine, a demographer at the French Institute of Health and Medical Research in Montpellier, who was not involved in the study.

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