As our prosperity rises, our mental health is on the decline—and fast. Rates of depression, anxiety, suicide, addiction, and other psychological disorders have skyrocketed in recent years, and nobody knows what to do about it.

Enter psychedelics: LSD, magic mushrooms, mescaline, ayahuasca—drugs you’d expect to find at a rave or a music festival, not in your psychologist’s office. But that may be about to change, as research in psychedelics increasingly shows their potential for treating psychological conditions.

Previously known as a food and nutrition expert thanks to books like The Omnivore’s Dilemma and In Defense of Food, author Michael Pollan switched tracks a bit for his latest project. His newest book, How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence, published last year, has been an integral part of de-stigmatizing the psychedelics conversation.

In a fascinating talk with The 4-Hour Workweek author Tim Ferris at South By Southwest earlier this month, Pollan shared insights from his research and his personal experiences.

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