In 1935, Einstein, Podolsky, and Rosen (EPR) presented an argument that they claimed implies that quantum mechanics provides an incomplete description of reality [1]. The argument rests on two assumptions. First, if the value of a physical property of a system can be predicted with certainty, without disturbance to the system, then there is an “element of reality” to that property, meaning it has a value even if it isn’t measured. Second, physical processes have effects that act locally rather than instantaneously over a distance. John Bell subsequently proposed a way to experimentally test these “local realism” assumptions [2], and so-called Bell tests have since invalidated them for systems of a few small particles, such as electrons or photons [3]. Now Paolo Colciaghi and colleagues at the University of Basel, Switzerland, have tested EPR’s argument for a larger system comprising clouds of hundreds of atoms [4]. Their results bring into question the validity of EPR’s local realism for mesoscopic massive systems.

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