Building on their groundbreaking research in epigenetics and transposable elements related to aging, scientists at Eötvös Loránd University have achieved a significant breakthrough in unraveling the molecular mechanisms of aging.
Drs. Ádám Sturm and Tibor Vellai of Eötvös Loránd University have achieved another significant breakthrough in the study of aging, expanding on their groundbreaking research into the epigenetics of aging and transposable elements. These new findings have deepened our understanding of the molecular mechanisms behind aging.
Their latest study, published in the International Journal of Molecular Sciences, reveals a novel epigenetic mechanism in mitochondrial DNA (mtDNA) that could revolutionize our approach to aging research and diagnostics.
In their previous landmark articles, “The mechanism of aging: primary role of transposable elements in genome disintegration” (2015) and “Downregulation of transposable elements extends lifespan in Caenorhabditis elegans” (2023), Dr. Sturm and Dr. Vellai established the crucial role of transposable elements in the aging process. Their current research expands on this foundation, uncovering a new layer of complexity in cellular aging.
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