INTRODUCTION

Silk is a natural protein-based material that has been used by humankind for over 5000 years (1). One of the two main components, silk fibroin (SF) has been exploited in recent decades for its ability to self-assemble into a range of fibril-based architectures that exhibit exceptional mechanical, optical, and excellent biocompatibility and biodegradability (24). Potential bioelectronic applications have been explored in which SF films are interfaced with van der Waals (vdW) solids, metals, or oxides, offering impressive electronic performance for next-generation thin-film transistors, memristors, human-machine interfaces, and sensors (47), provided that strategies can be developed to address challenges associated with the mismatch between the soft SF proteins and the hard, planar substrates (6).

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