Researchers have developed the first metal–organic framework (MOF) neuron that mimics brain-like behavior in aqueous environments by responding to dopamine. Unlike traditional solid-state devices, this MOF neuron reproduces key neural functions such as synaptic plasticity, integrate-and-fire signaling, and dopamine-tuned spike modulation.

In a proof-of-concept experiment, researchers used the neuron to control a robotic hand, where dopamine levels determined movement speed and strength. This breakthrough brings artificial neurons closer to realistic biological function and opens new possibilities for brain-inspired computing, biosensors, and advanced prosthetics.

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